About 4 results found for searched term "A 83-01" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5037 | A 83-01 | TGF-β Receptor |
| A83-01; A-83-01 | ||
| A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively).*The compound is unstable in solutions, freshly prepared is recommended | ||
| M54721 | A 83-01 sodium | TGF-beta/Smad |
| A 83-01 sodium is a potent inhibitor of TGF-β type I receptors ALK5, ALK4, and ALK7, inhibiting ALK5, ALK4, and ALK7-induced transcription with IC50 values of 12 nM, 45 nM, and 7.5 nM, respectively. | ||
| M24812 | Losatuxizumab | EGFR/HER2 |
| ABT-806 | ||
| Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC50s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFRC271A,C283A, 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers. | ||
| M28651 | ML401 | GPR/FFAR |
| ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity. | ||
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